연구논문

세부과제번호 2013M3A9D5072550 단계 1단계 1차년도
세부과제명 국가마우스표현형분석기반구축 공동 유/무 N
SCI여부 Y 게재년월 201405
논문제목 In-depth metabolic phenotyping of genetically engineered mouse models in obesity and diabetes
총저자명 Lee, Hui-Young; Jeong, Kyeong-Hoon; Choi, Cheol Soo
학술지명 MAMMALIAN GENOME 게재권(호) 25(9-10)
저널구분 국외 페이지수 2.883
참여연구원 - 연구책임자 성제경
과제기여도 10 PMID
사사기관수 IF (년도)
제1저자 교신저자
공동저자
초록
The world-wide prevalence of obesity and diabetes has increased sharply during the last two decades. Accordingly, the metabolic phenotyping of genetically engineered mouse models is critical for evaluating the functional roles of target genes in obesity and diabetes, and for developing new therapeutic targets. In this review, we discuss the practical meaning of metabolic phenotyping, the strategy of choosing appropriate tests, and considerations when designing and performing metabolic phenotyping in mice.
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